The Role IgM, IgG a, Complementary Factors C3, C4 and Latex assay in C-reactive Protein Positive Assay) in Perioniditis Patients

Abstract

Periodontal diseases include the common inflammatory disorders known as gingivitis and periodontitis, which are caused by microbes in the biofilms under the gums. The study aimed to identify the level of CRP, C3, C4, IgG and IgM in the serum of patients with periodontal diseases compared to its level in the healthy people. Sixty blood samples were collected from patients with Periodontal diseases , and 30 apparently healthy individuals who were considered as a control group .The current study showed that the prevalence of the disease was higher in females (n=33 ) than in males (n=27), ( 55.0% , 45.0%), respectively. As the highest rate of infection was within the age group from 30-39 years, at a rate of 36.7%, and the lowest was within 50-59 years at a rate of 3.3% .It was found through statistical analysis of the results that there are very high significant differences (p<0.001)between smoking and non-smoking patients. Chronic gingivitis had the highest prevalence rate of 51.7%, among other types. The results of the study also indicated that the CRP positivity in patients with Periodontal diseases was 68.3% and negative 31.7% . That the level of C3 and C4 in the sera of patients ,increased significantly P value (0.001,0.004) respectively, compared to its level in the sera of healthy subjects, where the mean ± standard deviation was [( 208.78 ± 55.40 and 138.67 ± 39.69);(43.65 ± 10.80 and 30.03 ± 9.81)] mg/dl, respectively. It was observed from the results of the study that the level of the IgM and IgG immunoglobulin of the patients had a very high significant increase (p <0.001) ,compared to the healthy group, [(228.37 ± 42.83 and 147.33 ± 13.86);(169.72 ± 68.32)] mg / dl, respectively.