Peculiarities of the Course of Joint Syndrome in Persons with Type 2 Diabetes Mellitus
DOI:
https://doi.org/10.51699/ijhsms.v2i5.1787Keywords:
diabetes, glycated hemoglobin, hypertension, osteoarthritis, osteoporosis, rheumatoid arthritisAbstract
Review. Currently, the problem of diseases of the musculoskeletal system and diabetes mellitus is characterized by an increase in medical and social importance, especially among the aging population. The International Diabetes Federation (IDF) predicts that if growth continues to accelerate, the total number of people with diabetes will surpass 435 million by 2030.Diabetes mellitus is characterized by a violation of all types of metabolism, which, of course, affects the course of diseases with damage to the musculoskeletal system. This is due to the fact that glucose is the main energy substrate for chondrocytes. Therefore, the problem of the relationship between diabetes mellitus and chronic joint diseases such as osteoarthritis, osteoporosis, rheumatoid arthritis is quite relevant today.
The study was carried out on the basis of the regional endocrinological dispensary of the Bukhara region of the Republic of Uzbekistan. The study involved 13 men and 45 women who were examined and treated in this hospital. The patients were divided by age: the mean age of men was 60 ± 8.6 years, and women were 67 ± 10 years old. Type 2 diabetes mellitus aggravates the course of articular syndrome in patients with combined pathology. The presence of type 2 diabetes mellitus in a patient with articular syndrome leads to increased pain syndrome, deterioration of joint function, and a higher frequency of secondary synovitis. Severe decompensation of carbohydrate metabolism (HbA1c> 10%) is associated with increased pain syndrome, more pronounced functional disorders and inflammatory changes in the joints in patients with articular syndrome in combination with type 2 diabetes mellitus.
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