Analgesic Effects of Lignocaine Alone and in Combination with Meloxicam Administered Epidurally in Dogs Undergoing Femoral Exposure

Authors

  • Adedoyin Olarewaju Ismail Faculty of Veterinary Medicine, Usmanu Danfodiyo University
  • Zainab Opeyemi Suleiman Faculty of Veterinary Medicine, Usmanu Danfodiyo University
  • Benjamin Emikpe Obukowho Faculty of Veterinary Medicine, University of Ibadan
  • Oyelowo Dayo Dorcas Faculty of Veterinary Medicine, University of Ibadan
  • Ayinde, Abayomi O University of Ibadan (Public Health Epidemiology)

DOI:

https://doi.org/10.51699/ijhsms.v2i1.876

Keywords:

Analgesic effect of lidocaine, Meloxicam administered, Dogs Femoral Exposure

Abstract

The experiment was done to evaluate and compare the analgesic effects of lignocaine alone and in combination with meloxicam administered epidurally in dogs undergoing femoral exposure. Eight (n=8) apparently healthy Nigeria local dogs with average weight 9.6kg were used for the research. They were randomly grouped into two groups (A and B) of four dogs each. Pain assessment was done using physiologic parameters (temperature, pulse rate and respiratory rate), haematologic parameters (total WBC count and differential neutrophil count) mined using clinical algometer at o minute and subsequently and 30, 60, 90,120,150 and 180 minutes respectively. The mean values of each parameter were subjected to student t-test with p-values (0.05).Pain threshold showed no significant difference between group A and B (p>0.05).There was no significant difference between the two groups with respect to rectal temperature (p>0.05). For pulse rate, significant difference was observed between group A and B(p<0.05).For respiratory rate, there was significant difference between the two groups (p>0.05).Differential neutrophil count statistical analysis revealed no significant difference between the two groups (p>0.05).There was no significant difference at any time interval between the two groups with respect to Complete White Blood Cell Count(p>0.05).It was concluded that combined lignocaine and meloxicam administered epidurally rendered prolong analgesia than use of lignocaine alone without any postsurgical complication.

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References

Aiyedun, O. (2012). Identification and analysis of dogs use, management practices and implication for rabies control in Ilorin, Nigeria. Sokoto Journal Of Veterinary Science, 10(2):1-6

Aliu, Y. O. (2011). Textbook of Veterinary Pharmacology (1sted.), Tamaza Publishing Company, Kaduna. Pp 188-221

Anne, F., Paul, C. and Magdoline, A. (2018). Consequences and Management of Canine Brachycephaly in Veterinary Practise. Journa of Biomedical Science, 9(3): 8-25

Barbara, F. (2004). Textbook of Veterinary practise, pharmacy guide for veterinarians and pet owners; (3rd ed.) ,vol.1. Swedesboro publishing company, Sweden. pp 1-3

Bednarek, D., Paduch, R.,Kondracki, M. (1999). Effect of steroidal andnon-steroidal anti-inflammatory drugs on the cellular immunity of calves with experimentally-induced local lung inflammation.NLB Journal, 71(1):1-15

Brickner, I. (2002). The impact of domestic dogs (Canis familiaris ) on wildlife and conservation, International Journal for the Study of Animal Problems. 4(1): 44-58

Bromley,L.(2006) Pre-emptive Analgesia and Protective Premedication. National Library of Medicine Journal , 60(7): 336-40

Burno, P., Amy, K., Noel, M. (2021). Open approach to femoral shaft, Principle, Skin incision and fracture management in small animals. http://surgeryreference.aofundation.org access on 28thaugust,at 7:22 pm,Pp 1-3.

Christian,B., Jan, R., Hugo,V., Aken, M.W. and Alexander, Z.(2014) Lidocaine Reduces Neutrophil Recruitment By Abolishing Chemokine-Induced Arrest And Transendothelial Migration In Septic Patients. The Journal of Immunology. 192(1):367-376

Christiana, T., Rebecaboden, M., K. (2018),Decrease Lymphocytes and Increased Risk for Infection are Common in Endogenous Pediatric Cushing Syndrome, PediatrRes Journal. 83(2):431-437

Daniela M., Melendez, Sonia , M., Edmond A., P. (2018). Effect of meloxicam and lignocaine administered alone or in combination on pain and distress during and after knife castration in weaned beef calves, Jounalplos. 13 (11):1-3

Engelhardt, G. (1996) ,General Pharmacology Of Meloxicam: Efect on blood rate ,ECG,respiratory minute volume and interaction with paracetamol, pirenzepine, chlorthalidine,phenprocoumon and tolbutamide. NLB Journal. 27(4): 67-88

Gary, O. (2004). EpiduralAnaesthesia and Analgesia. Veterinary Anaesthesia and Analgesia Support Group, Texas (USA) available at https://vasg.org.bio.cv accessed on 28thSeptember, 2021 at 2:20pm Pp1-10.

Hanse, C., Mark, V., Boswell, A., M., Joshua , A.,H. (2003). Epidural Steroid in the Management of Chronic Spinal Pain And Radiculopathy, National Center for Biotechnology Information Journal. 6(3):19-34

Hassan, A. Z and Hassan, F. B. (2003). An Introductory to Veterinary Practice, (2nd ed.). Ahmadu Bello University Press Limited,Zaria. Pp.64-65

Hellyer, P. Roman, I., Brunt, J., Downing,R. and Hagedorn, J., E. (2007). Pain management guidelines for dogs and cats, Journal of Feline Medicine and Surgery. 9:466-480

Ishola, O.,O.(2016) Management And Socio Economic Determinant Of Profitability In Dog. Sokoto Journal Of Veterinary Science. 14(1):1-3

Jagdeep, S., Ruchi, G., Jasveer, S. (2018) A Comparative Study Of 0.25% Levobupivacaine ,0.25% Ropivacaine, and 0.25% Bupivacaine in Paediatric Single Shot Caudal Block . Avalable at https:www.ncbi.nlm.nih.govpmc/articles India, accessed on 9th September , 2021 at 7:20pm .

King, A. N. (2017). Textbook Of Veterinary Clinical Pathology, (1st ed.) Spectrum Book publisher Limited, Ibadan, Pp 47-131

Lynn, J., K. Dean, H., R. (2006), Epidural Analgesia in Dog ,Journal of food and agriculture organization of the United State , 33(4): 246-257

Mathew, K. (2014):Guidelines for Recorgnition, Assessment and Treatment of pain. Journal of Small Animal Practice. 55(6):10-68

McMillian (2003). Guidelines for the Assessment and Management of pain in Rodents and Rabit. Available at http:www.reseach .fsu.edu/media Florida(USA),accessed on 9th September ,2021 at 7:56 pm Pp 1-24

Melendez, D., M. Sonia, M. Edmond, A., J. Johaan, F. (2018). Effect Of Meloxicam And Lignocaine Administered Alone Or In Combination On Indicators Of Pain And After Knife Castration In Beef Calves, PLOS Journals. 13(11):27-29

Olaifa, A. K and Oluranti, O. I. (2018). The Use Of Epidural Anaesthesia Over General Anaesthesia In Ruminants, Concept of Dairy of Veterinary Science journal. 1(3):68-70.

Randy, K. (2003). A Complete Blood Count Most Effective Tracks of a Dog’s Response to Treatment. WorldDogJournali, 4(1):1-25

Salisu, B., Ozigi, O. N., Yakubu A. S., Junaidu, I., Zainab, B. M., Umar A. S., Nura, A. and Hassan A. B. (2020). Comparative Analgesia Effect of Lignocaine And Meloxicam For Post-oprative Pain Management in Cats. Scholarly Journal of Biological Science, 9(2):25-31

Sansi, J.,Aderoke, A. (2012). Evaluation of three Methods For Routine Diagnosis Of Leptospirosis In Nigeria. Journal of Basis and Applied Science, 7:27-30

Savolaine, P., Jing Luo, Y., Joakim, L. (2002).Genetic Evidence for East Asian Origin Of Domestic Dogs. Sciencemag Journal, 298(52):1611-1633

Sayyed, T., Mehran, Z., Farshad, N., Ahmad, D. (2015) .Relation Of Cortisol, Norepinephrine, And Epinephrine Levels With War Induced Posttraumatic Stress Disorder In Father And Their Offspring . Brazilian Journal of Psychiatry, 35(2)

Sheng, C.,K. Chia,S.,L. (2017) Caudal Epidural Block :An Update Review Of Anatomy And Techniques . BioMed Reseach International , 20(1):1-5

Slatter, D., H. (2003) Text Book of Small Animal surgery (3rd ed.), Management Philadelpia publisher, Saunder, Pp 1-10

Spenser, L., Randall, L., Carpenter, M., D., Joseph , M.N.(1995) Epidural Anaesthesia and Analgesia : Their Roles in Post Operative Outcome. American Society of Anaesthesiologists Publications and Journals. 82: (1474 -1506).

Srinivasa, C., V., Suresh, Y., J. Kumar, W.,P.(2012) Free Flexural Vibration Studies On Laminated Composite Skew Plate .International Journal Of Engineering ,Science And Technology. 4(4): 13-24

Subhanullah, Muhammad Shuaib, Sardar H., ZaheerAbbass, NasarKhan(2017): Effect of Xylazine And Ketamine On Pulserate, Respiratory rate And Body temperature in dogs, International Journal Of Avian, 2(4):137-139.

Swindle M., M.(1998). Comparative Anatomy and Physiology of the Pigs.Scandinavian Journal of Laboratory Animal Scioence. 25(1):11-21

Teng-YU, T., Shao-Kuang C., Po-Yen C., LihSeng-yeh (2013).Comparison postoperative effect between lidocaine infusion, meloxicam,and their combination in dogs undergoing ovariohysterectomy, National Center for Biotechnology Information .USA National Library Journal., 40(6):6-22

Troels, S., J. (2008). Neuropathic pain redefining and grading system for clinical and research purpose.International Association for the Study of Pain Journal. 3(2):1

Wilkins and Williams (1996). Textbook of Small Animal Surgery (3rded.).vol.1., Elsiever Health Science Publisher 3rd ed. Baltimore Pp 2513-2517

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Published

2023-01-10

How to Cite

Ismail, A. O. . ., Suleiman, Z. O. . ., Obukowho, B. E. . ., Dorcas, O. D. . ., & O , A. A. . (2023). Analgesic Effects of Lignocaine Alone and in Combination with Meloxicam Administered Epidurally in Dogs Undergoing Femoral Exposure. INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES, 2(1), 1–12. https://doi.org/10.51699/ijhsms.v2i1.876

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