Modern Treatment Regimens for Chronic Obstructive Pulmonary Disease
DOI:
https://doi.org/10.51699/ijhsms.v1i6.691Keywords:
chronic obstructive pulmonary disease, principles and schemes of treatmentAbstract
According to modern concepts, chronic obstructive pulmonary disease (COPD) is "a disease characterized by airflow limitation that is not fully reversible; airflow limitation is progressive and associated with a pathological inflammatory response of the lungs to the action of inhaled pathogenic particles or gases. The primary target of COPD is the respiratory organs. The main clinical manifestations of COPD are cough, sputum production and progressive dyspnea. External respiratory function in COPD is characterized by the emergence of slowly increasing airflow restrictions with progressive reduction of forced expiratory volume per second (FEF1) and Hensler index (FEF1/FEL) due to increased resistance in the airways with subsequent deterioration of gas exchange in the lungs. Complications of COPD are known: pulmonary hyperinflation (pulmonary emphysema), chronic respiratory failure, secondary pre-capillary pulmonary hypertension and chronic pulmonary heart disease, which should be considered as natural manifestations of the natural course of COPD.
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