Effectiveness of Sugar-Reducing Drugs on the Kidneys in Patients with Type 2 Diabetes Mellitus

Abstract

Diabetes mellitus is becoming a real epidemic these days as it affects many people in our population. According to many authors, the number of patients with this pathology will double in 50 years. Wrong diet, bad habits, wrong way of life aggravates the situation of these patients. Stress and other factors also have a detrimental effect on human health, many literature provides examples stress-dependent metabolic disorders, including diabetes mellitus [1,2,5,6]. Diabetes is the most common cause of chronic kidney disease (CKD). Both conditions usually coexist. Glucometabolic changes and concomitant dialysis in diabetes and CKD make it difficult to lower glucose levels, increasing the risk of hypoglycemia. Glucose-lowering drugs have mainly been studied in people with near-normal kidney function. To guide treatment, it is important to characterize the current knowledge of glucose-lowering agents in CKD (chronic kidney disease) [1, 2]. Currently, the level of GFR (glomerular filtration rate) is recognized as the best method for assessing kidney function in general, both in healthy individuals and in type 2 DM [3, 4,7].