Comparing the Effects of Different Flow Rate of Fresh Gas on Patient Hemodynamic Stability and Depth of Anesthesia

Abstract

More general anaesthesia with lower fresh gas flow rates is needed to reduce environmental contamination and treatment costs. Reducing or eliminating fresh gas administration improves patient care by keeping the highest anaesthesia safety and quality standards and reducing emissions. The increasing use of low fresh gas flow rates addresses environmental concerns and ensures excellent anaesthesia patient outcomes. This study examined how the unique low-flow anaesthesia regimen affected hemodynamic stability throughout medical procedures. One hundred consecutive people were used for this experiment. A group of patients received two litres per minute of high flow anaesthesia (HFA) while another received one litre per minute of low flow (LFA). Surgery took up to two hours for each research subject. The bispectral index (BIS), heart rate (HR), blood pressure, end-tidal carbon dioxide levels, haemoglobin oxygen saturation (SaO₂), and inhalational anaesthetic agent concentrations like isoflurane, nitrous oxide (N₂O), and oxygen (O₂) were closely monitored and recorded during the procedures. The two groups had significantly different heart rates, SaO₂ levels, and systolic and diastolic blood pressure. The two groups' BIS scores were similar, showing that low-flow anaesthesia patients were not more alert during surgery. In addition, the high-flow and low-flow anaesthesia groups had statistically significant differences in end-tidal anaesthetic concentrations at 5, 10, 15, and 60 minutes and after surgery. To conclude, low-flow and high-flow rate general anaesthesia approaches maintain hemodynamic stability and provide the optimum anaesthesia for patients. The current study stresses the importance of continuously monitoring and controlling anaesthesia administration methods to optimise patient outcomes and procedural safety. This study adds to the knowledge of anaesthetic methods and their influence on clinical management and patient care in healthcare.