Cytokines as Predictors of Adverse Conditions in Premature Children from Complicated Pregnancy

Abstract

This paper presents information on the cytokines IL-6 and IL-8 in premature newborns with perinatal CNS lesions and intrauterine infection, depending on gestational age and the severity of preeclampsia in pregnant women. It has been established that an increase in blood IL-6 has a diagnostic value in the pathogenesis of perinatal CNS lesions, and an increase in blood IL-8 indicates the progression of neonatal infections in premature babies from mothers with preeclampsia. An increase in IL-6 in the blood has been proven to be of diagnostic value in the pathogenesis of perinatal lesions of the central nervous system with the highest probability at a gestational age of 34-37 weeks, and an increase in IL-8 in the blood indicates the progression of neonatal infections in premature infants born at a gestation period of 28-33 weeks from mothers with severe preeclampsia and has a high correlation between gestational age and severity of preeclampsia.