Immunological Features of Mixed Saliva in Patients with Gastrointestinal Disease
DOI:
https://doi.org/10.51699/ijhsms.v1i4.293Keywords:
mixed saliva, patients with GI disease, antimicrobial peptideAbstract
The aim of this article was to study the immunological features of mixed saliva in patients with gastrointestinal tract disease. 140 patients with gastrointestinal pathology were examined. Pro- and anti-inflammatory cytokines (IL-1, IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-a) and alpha-defensin 1-3 were studied. When studying the content of cytokines and antimicrobial peptide in the mixed saliva of patients with GIT disease, the predominance of proinflammatory cytokines over anti-inflammatory ones and the decrease of antimicrobial peptide level were noted, which may activate bone resorption?
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