Significance of Gene Xpert Mbt/Rif Test in Tuberculosis Diagnostics
DOI:
https://doi.org/10.51699/ijhsms.v2i10.2652Keywords:
Gene Xpert MTB/RIF, tuberculosis, patient, microscopy, culture mediaAbstract
Tuberculosis is an infectious disease, and its problem remains relevant throughout the world. It is the second leading cause of death among infectious diseases. Microscopy, culture media, and drug susceptibility testing are the standard methods used in the laboratory diagnosis of tuberculosis worldwide, but they are time-consuming processes, taking up to eight weeks to make a diagnosis. The urgent issue of modern phthisiology is the development of new fast and reliable methods of diagnosis of tuberculosis infection. In recent years, the Gene Xpert MBT/RIF system has been widely used. The purpose of the study was to determine the significance of the Gene Xpert MBT/RIF test in the diagnosis of pulmonary tuberculosis. The study showed the high specificity and relatively high sensitivity of the Gene Xpert MTB/RIF test, which showed that it can serve as an additional method in the comparative diagnosis of tuberculosis and other lung diseases. In addition, the Gene Xpert MTB/RIF test is a more effective screening method than conventional methods in reducing the time to diagnose tuberculosis, as well as in detecting rifampicin resistance. The Gene Xpert MTB/RIF is a fully automated method that helps ensure the biosafety of laboratory staff performing tuberculosis testing.
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