Pathogenic Influence of Pesticides on the Thyroid Gland of Offspring under the Conditions of Their Exposure through the Mother's Body during Pregnancy and Lactation
DOI:
https://doi.org/10.51699/ijhsms.v2i9.2590Keywords:
Pesticides, thyroid glands, chronic intoxicationAbstract
The aim of the study was to identify the toxic effect of intrauterine and early postnatal exposure to pesticides on the development of the endocrine system of offspring. The thyroid gland of the offspring obtained from mothers with chronic poisoning with pesticides vigor and fastkine was examined on 1-30 days after birth using electron microscopic methods. It was revealed that intoxication of the mother's body significantly slows down the pace of postnatal formation of secretory follicles. Ultrastructural changes were found in the form of disorganization of the granular endoplasmic network and destruction of other cytoplasmic organelles of thyrocytes. These changes are a morphological substrate of thyroid dysfunction that occurs in the postnatal ontogenesis of the organ in conditions of chronic intoxication.
Toxic effects of pesticides on the endocrine systems of offspring under the conditions of their exposure through the mother's body during pregnancy and lactation
The thyroid gland of posterity, got from full-grown with chronic intoxication by pesticides vigor and fastokine, has been studied on 1-30 day after birth using electron microscopy methods. It is revealed that intoxication of maternal organism vastly slows the rates of postnatal formation of secretory follicles. It is expected that discovered ultrastructural changes of the thyrocytes are morphological substratum of the dysfunctions of the thyroid gland.
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