Violation of Mineral Metabolism and Vascular Remodeling in Chronic Kidney Disease (CKD)

Abstract

Violation of mineral metabolism and vascular remodeling in Chronic kidney disease (CKD) is one of the formidable and common complications of this condition. One of the main risk factors for remodeling is a violation of mineral metabolism, namely phosphorus-calcium. Abnormalities in the metabolism of calcium, phosphorus, parathyroid hormone (PTH) and vitamin D lead to ectopic, i.e. vascular or tissue calcification. To date, studies concerning ectopic calcification are of great interest to researchers, which is due to both the improvement of methods for detecting calcification and the sharp progression of its prevalence due to the pandemic of chronic non-communicable diseases, including CKD