Current State of Autoimmune Thyroiditis Problem
DOI:
https://doi.org/10.51699/ijhsms.v2i5.1783Keywords:
autoimmune thyroiditis, hypothyroidism, pathogenesis of autoimmune thyroiditis, organization of medical careAbstract
The review provides up-to-date data on pathogenetic mechanisms, diagnostic capabilities, and features of organizational and medical measures related to autoimmune thyroiditis (AIT). AIT is a polyethological disease, which is based on the influence of environmental factors, genetic predisposition and violation of immune regulation.
The review analyzes the association of AIT with an imbalance of a number of trace elements involved in the synthesis of thyroid hormones and affecting iodine metabolism. The results of studies that established the nature of immune disorders in AIT and hypothyroidism in the form of violations of subpopulations of lymphocytes, pro-inflammatory and anti-inflammatory cytokines, changes in the mechanisms of apoptosis, which were proposed for use as predictors of the severity of thyroid immune inflammation and hypothyroidism are presented. The criteria for selecting patients with an increased risk of developing complications in AIT remain unclear, which makes it necessary to develop and implement additional organizational and medical measures to monitor this population of patients and assess their quality of life.
Downloads
References
Karlovich NV, Mohort TV, Voroncova TV. Rasprostranen-nost' i harakter autoimmunnoj patologii shhitovidnoj zhelezy u lic molodogo vozrasta s saharnym diabetom tipa 1. Probl. jendokrinologii. 2005;1:19-24.
Tomer Y, Peters JJ. Mechanisms of autoimmune thyroid diseases: from genetics to epigenetics. Annu. Rev. Pathol. Mech. Dis. 2014;9:147-56.
Colin MD, Gilbert HD. Chronic autoimmune thyroiditis. New. Engl. J. Med. 2016;335:99-107.
Mohort TV, Kolomiec ND, Petrenko SV, Fedorenko EV, Mohort EG. Jodnyj deficit: gde my teper'? (Jeffektivnost' belorusskoj strategii likvidacii jodnogo deficita: 15-letnij opyt). Mezhdunarodnyj jendokrinologicheskij zhurnal. 2015;66(2):13-19.
Korytko SS, Hmara IM, Salko OB, Antipov VV. Bolezni jendokrinnoj sistemy v Belarusi - statisticheskie i demograficheskie sopostavlenija. Medicinskie novosti. 2013;3:42-48.
Grjaznova MA, Hamnueva LJu. Osobennosti citokinovoj reguljacii pri autoimmunnoj patologii shhitovidnoj zhelezy. Zhurnal nauchnyh statej «Zdorov'e i obrazovanie v XXI veke». 2017;19(7):33-39.
Dedov II, Troshina EA, Antonova SS. Autoimmunnye zabolevanija shhitovidnoj zhelezy: sostojanie problemy. Probl. jendokrinologii. 2002;2: 6-13.
Ivanova OI, Solomina MS, Logvinov SV, Solomatina TV. Sovremennye aspekty jetiologii i patogeneza hronicheskogo autoimmun-nogo tireoidita. Sibirskij onkologicheskij zhurnal. 2006;17(1):55-60.
Wiersinga WM. Clinical Relevance of Environmental Factors in the Pathogenesis of Autoimmune Thyroid Disease. Endocrinol Metab. 2016;31:213-22.
Vojtovich TN, Al'ferovich EN. Vlijanie nasledstvennyh faktorov v formirovanii patologii tireoidnoj i reproduktivnoj sistem u pacientov s zabolevanijami shhitovidnoj zhelezy. Medicinskij zhurnal. 2012;3:18-21.
Chernobyl Forum. Chernobyl's Legacy: Health, Environmental and Socio-Economic Impacts and Recommendations to the Governments of Belarus, the Russian Federation and Ukraine. The Chernobyl Forum: 2003-2005. Vienna: IAEA, 2006.
Espenbetova MZh, Zhumanbaeva ZhM, Amrenova KSh. Chastota vstrechaemosti patologii shhitovidnoj zhelezy u zhitelej ter-ritorij, prilegajushhih k byvshemu Semipalatinskomu ispytatel'nomu jadernomu poligonu. Academy. 2017;11(26):64-68.
Drozd V. Screening of thyroid status in children exposed to ionizing radiation in utero and the first year of life as a result of the Chernobyl accident. Int. J Rad Med. 2003;5:167-179.
Yamashita S, Shibata Y. Chernobyl: A Decade. Proceedings of the Fifth Chernobyl Sasakawa Medical Cooperation Symposium, Kiev, 14-15 October 1996. Amsterdam: Elsevier Science B.V., 1997.
Malenchenko AF, Vasilenko IJa, Vasilenko OI. Obmen joda v techenie patologicheskih processov v shhitovidnoj zheleze u ljudej v regionah zobnoj jendemii pri porazhenii radiojdom. Radiacionnaja biologija. Radiojekologija. 2007;47(4):435-443.
Andrjukov BG, Gvozdenko TA, Dem'janenko NB. Izbytok joda v organizme - jekologicheskij faktor riska razvitija autoimmunnyh zabolevanij shhitovidnoj zhelezy? Zdorov'e. Medicinskaja jekologija. Nauka. 2015;60(2):6-16.
Shabalina EA, Morgunova TB, Orlova SV, Fadeev VV. Selen i shhitovidnaja zheleza. Klinicheskaja i jeksperimental'naja tireoidologija. 2010;7(2):7-18.
Mazopakis EE, Papadakis JA, Papadomanolaki MG. Effects of 12 months treatment with L-selenomethionine on serum anti-TPO levels in patients with Hashimotos thyroiditis. Thuroid. 2007;17:609-12.
Fan Y, Xu S, Zhang H. Selenium supplementation for autoimmune thyroiditis: a systematic review and meta-analysis. Int J Endocrinol. 2014: Article ID 904573 http://dx.doi.org/10.1155/2014/904573.
Van Zuuren EJ, Albusta AY, Fedorowicz Z. Selenium Supplementation for Hashimoto's Thyroiditis: Summary of a Cochrane Systematic Review. Eur Thyroid J. 2014;3:25-31.
Rustembekova SA, Baraboshkina TA. Mikrojelementozy i faktory jekologicheskogo riska: Monografija (glavy 2,4-7, razdel 8.2). Moskva, RF: Universitetskaja kniga. Logos; 2006. 112 s.
Sharipova ZF, Farhutdinova LM. Mikrojelementnyj status volos pri zabolevanijah shhitovidnoj zhelezy v zavisimosti ot ee funkcional'nogo sostojanija i ego svjaz' s immunologicheskim sta-tusom. Vestnik novyh medicinskih tehnologij. 2006;13(3):124-124.
Kandror VI. Molekuljarno-geneticheskie aspekty tireoidnoj patologii. Probl. jendokrinologii. 2001;5:3-10.
Sunhalyrova TK, Dodohov VV, Solov'eva NA, Pavlova NI, Fillipova NP, Neustroeva LM. Geneticheskie faktory pre-draspolozhennosti k autoimmunnym tireopatijam. Jakutskij medicinskij zhurnal. 2018;2:106-09. DOI 10.25789/YMJ. 2018.62.32.
Zhurakulova Zebuniso Ahtamovna. Secondary infertility in women of reproductive age with hypothyroidism|| ACADEMICIA: An International Multidisciplinary Research Journal|| 2022, Volume : 12, Issue: 5; p: 649-653 ISSN : 2249-7137 DOI : 10.5958/2249-7137.2022.00424.4
Jurakulova Zebuniso Akhtamovna. PRIMARY INFERTILITY IN WOMEN OF REPRODUCTIVE AGEWITH HYPOTHYROIDISM // EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE. Vol. 2 No. 5 (2022) EJMMP ISSN: 2795-921X. P 165-16827.
Zhurakulova Zebuniso Ahtamovna. Diffusetoxic Goiter, Diagnosis and Treatment // INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES . ISSN: 2833-7433 Volume 1 | No 6 | Dec-2022. P 331-336
Yaxyayeva Hilola Sharifovna. Thyroid Cancer Diagnostics, Classification, Staging. Journal of Innovations in Social Science 2021— Р. 63-69
