Chemical Composition and Antimicrobial Activity of the Essential Oil of the Plant Phlomoides Isoсhila

Authors

  • Akramov D. Kh Samarkand State Medical University, 18, Amir Temur Street, 140100 Samarkand, Uzbekistan
  • Jabbarov Sh. A Samarkand State Medical University, 18, Amir Temur Street, 140100 Samarkand, Uzbekistan
  • Ashurova L. N Institute of Chemistry of Plant Substances, acad. S.Yu.Yunusova AS RUz, Mirzo Ulugbek str. 77, 100170 Tashkent, Uzbekistan
  • Akramov T. R Teacher of chemistry at the 81st general education school, Urgut district, Samarkand region

DOI:

https://doi.org/10.51699/ijhsms.v2i3.1307

Keywords:

Phlomoides isochila, essential oil, antimicrobial activity

Abstract

For the first time, the chemical composition of the volatile components of the aerial parts of the Phlomoides isochila plant growing in the Republic of Uzbekistan was studied. The main components of the essential oil were β-Thujone (29.76%), Camphor (18.03%) and 1,8-Cineol (12.12%). In vitro studies of antibacterial and antifungal activity have shown that Ph. isochila exhibits a significant antibacterial effect against gram-positive bacteria Bacillus subtilis (15.04±0.10) and Staphylococcus aureus (10.08±0.12).

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References

Eremostachys isochila. Флора Узбекистана т. 5, ст. 345.

R. P. Adams. Identification of Essential Oil Components by Gas Chromatography /Mass Spectrometry Allured Publishing Corporation, Carol Stream, Illinois, US, 2007, 804 pp.

V. I. Babushok, P. J. Linstrom and I. G. Zenkevich. J. Phys. Chem. Ref. Data, 40, 1 (2011).

Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Disk Susceptibility Tests. CLSI document M02. 13th Edition. PA, USA. 2018.

S.A. Sasmakov, Zh.M. Putieva, Sh.S. Azimova, U.Lindequist. Asian J. Trad. Med., 7(2), 73-80 (2012).

N.Z. Mamadalieva, F.S. Youssef, M.L. Ashour, D.Kh. Akramov, S.A. Sasmakov, N.Sh. Ramazonov, Sh.S. Azimova. A comparative study on chemical composition and antimicrobial activity of essential oils from three Phlomis species from Uzbekistan. Natural Product Research, 35(4): 696-701 (2021).

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Published

2023-03-26

How to Cite

Kh, A. D. ., A, J. S. ., N, A. L., & R, A. T. (2023). Chemical Composition and Antimicrobial Activity of the Essential Oil of the Plant Phlomoides Isoсhila. INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES, 2(3), 73–76. https://doi.org/10.51699/ijhsms.v2i3.1307

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