The Significance of Polymorphism of Genes Involved in the Stages of Pharmacokinetics of Drugs Used for the Treatment of Peptic Ulcer Disease

Authors

  • Ochilova Gulrukh Saidovna Department of Pharmacology and clinical pharmacology, Bukhara state medical institute Abu Ali ibn Sino, Bukhara, republic of Uzbekistan
  • Ochilov Alisher Kamilovich Department of Pharmacology and clinical pharmacology, Bukhara state medical institute Abu Ali ibn Sino, Bukhara, republic of Uzbekistan

DOI:

https://doi.org/10.51699/ajsld.v2i1.935

Keywords:

pharmacotherapy, chronic gastritis, H. pylori, CYP2C19 gene, genotypes, personification of pharmacotherapy

Abstract

The article notes that pharmacotherapy taking into account the patient's genotype is a young direction that contributes to improving the safety and effectiveness of treatment with proton pump inhibitors. Determination of the patient's genetic affiliation by polymorphisms of the MDR-1 and CYP2C19 genes allows us to initially determine the tactics of treatment with proton pump inhibitors in patients with acid-dependent diseases.

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Published

2023-01-20

How to Cite

Saidovna , O. G. ., & Kamilovich , O. A. . (2023). The Significance of Polymorphism of Genes Involved in the Stages of Pharmacokinetics of Drugs Used for the Treatment of Peptic Ulcer Disease. American Journal of Science and Learning for Development, 2(1), 118–121. https://doi.org/10.51699/ajsld.v2i1.935

Issue

Vol. 2 No. 1 (2023): AMERICAN JOURNAL OF SCIENCE AND LEARNING FOR DEVELOPMENT (AJSLD)

Section

Articles