Activity Ethanolic and Methanolic Extracts of Arthrospira Platensis on Pathogenicity of Staphylococcus Aureu Sand Streptococcus Mutans

Abstract

This study is found out the bioactive compounds in Arthrospira platensis alga that is obtained from the Environmental Research Center\ University of Technology. The extraction process is done with ethanol 99% and methanol 99% as solvents. Staphylococcus aureus and Streptococcus mutans are obtained from Al-Ameen Center for research and   advanced biotechnology in the Holy City of Najaf from urine. which is gram-negative To evaluate the antibacterial activity are used four concentrations (0.5, 1.5, 3, 15) mg\ml for each extract with three replicates by agar well diffusion method.

As a result, all concentrations make bacterial inhibition zone and affected more by increasing the extract concentration and highest inhibition rate is for ethanolic extract with an (15.08 ±2.38mm) while the methanolic extract with an average (14.28±2.53mm) And appeared  cultivated on Congo Red Agar medium is able to change the medium color from pink or red to black, indicating their ability to form biofilms, and the ethanolic extract had an anti-biofilm effect.